WebAug 29, 2024 · Background: Cuproptosis is a novel type of cell death induced by copper. Cuproptosis-associated genes play a crucial part in oncogenesis and the growth and metastasis of tumors. However, the correlations among cuproptosis-associated genes, overall survival, the tumor microenvironment, and drug sensitivity remain unclear. … WebApr 14, 2024 · When a microbe lands on copper, ions blast the pathogen like an onslaught of missiles, preventing cell respiration and punching holes in the cell membrane or viral coating and creating free ...
Copper induces cell death by targeting lipoylated TCA …
WebBesides apoptosis, pyroptosis, necroptosis and ferroptosis, a new form of programmed cell death was discovered and reported as cuproptosis, copper-induced cell death. As a cofactor for essential enzymes, copper is an indispensable trace metal to maintain protein functions. Intracellular copper concentration remains low under homeostatic control. WebCopper (Cu) is a bioelement essential for a myriad of enzymatic reactions, which when present in high concentration leads to cytotoxicity. Whereas Cu toxicity is usually assumed to originate from the metal's ability to … gacha life ggg
Copper induces cell death by targeting lipoylated TCA cycle …
WebApr 1, 2024 · In a recent study published in Science, Tsvetkov et al. discovered a new form of copper-dependent cell death termed cuproptosis [7]. This is nonapoptotic cell death that involves intracellular ... WebNov 11, 2024 · of the literature on copper-induced cell death to understand the development of copper-induced cell death better and identify potential new research directions. Methods: With the help of Cite Space software, … WebApr 21, 2024 · Correction to Tsvetkov et al., Science 375, 1254 (2024) In the Research Article “ Copper induces cell death by targeting lipoylated TCA cycle proteins ,” the photomicrograph showing a representative image of a tumor with low expression of FDX1 in Fig. 4C was incorrect. gacha life gems