WebTraductions en contexte de "Polypyrimidine" en anglais-français avec Reverso Context : Polypyrimidine oligonucleotides can bind to tracts of contiguous purines in double-stranded DNA to form triple-stranded complexes. WebThe polypyrimidine tract binding (PTB) protein family of RBPs are important posttranscriptional regulators of gene expression. In the nervous system, the function and importance of PTB protein 2 ...
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WebMay 26, 2010 · Background Prolonged periods of high glucose exposure results in human islet dysfunction in vitro. The underlying mechanisms behind this effect of high glucose are, however, unknown. The polypyrimidine tract binding protein (PTB) is required for stabilization of insulin mRNA and the PTB mRNA 3′-UTR contains binding sites for the … WebFIGURE 1 Regulation of polypyrimidine tract-binding protein 1 (PTBP1) and pyruvate kinase M (PKM) isoforms by microRNAs: schematics. Brain and muscle-specific miRNAs bind to the 3′ UTR of PTBP1 and downregulate PTBP1 expression. PKM1 dominance is induced through the suppression of alternative splicing in these healthy organs. highline ballroom seating chart
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WebAug 1, 2008 · Polypyrimidine tract-binding protein 1 (PTBP1) is a multifunctional RNA binding protein that is best characterized for its activity in alternative splicing via selective splice-site utilization of ... WebTraductions en contexte de "polypyrimidine tract" en anglais-français avec Reverso Context : Upstream (5'-ward) from the AG there is a region high in pyrimidines (C and U), or polypyrimidine tract. WebHere we show that genes encoding critical presynaptic proteins are transcribed at a detectable level in both neurons and nonneuronal cells. However, in nonneuronal cells, the splicing of 3′-terminal introns within these genes is repressed by the polypyrimidine tract-binding protein (Ptbp1). highline ballroom new york ny